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Qi Zhou was born in 1970 in Harbin City, Heilongjiang Province,received a PhD in Physiology & Embryology from Northeast Agriculture University, China, 1996 (Thesis: Nuclear transfer and serial nuclear transfer research in rabbit). In 1997-1999 he held a postdoctoral and Associate Professor position in the Institute of Developmental Biology, Chinese Academy of Sciences (CAS), and in 1999-2002 he was a postdoc and Project leader within the group of Prof. J.P. Renard (Developmental Biology and Reproduction, INRA, JouyenJosas, France). In 2001 he was offered a 100 talent position in the Institute of Zoology, CAS, where he is currently Professor of Developmental Biology, vice director of State Key Lab of Reproductive Biology.
As a developmental biologist, Dr. Zhou’s research interest is to study the mechanisms of differentiation and dedifferentiation, particularly, cellular plasticity and totipotency of the stem cells, and the reprogramming mechanisms of the somatic cells. In addition, he also focuses on the translation from fundamental researches towards medicine and technology applications to finally promote the development of regenerative medicine.
Up to now, Dr.Zhou is recognized for his numerous scientific achievements in cloning, stem cells and regenerative medicine research. He created the world’s first cloned rat and was the second to report cloned mouse. He also generated cloned rabbit, bovine, goat, ferret and the first Chinese transgenic monkey. Dr. Zhou established animal models for many human diseases, such as CF and AIDS, and indicated potential high risk of neurodegenerative disorders of PGD offsprings. He has also established hundreds of stem cell lines from different mammalian species. Notably, for the first time in the world, he proved the true pluripotency of iPS cells by producing viable mice through tetraploid completion and identified a genomic region of mice, which can serve as a marker to evaluate the pluripotency status of pluripotent cells. These valuable animal and cellular models provide important platforms and resources to promote research in the development of regenerative medicine.
Dr. Zhou’s work has resulted in numerous publications in toptiered scientific journals, including Nature, Science, PNAS, Journal of Biological Chemistry, MCP, Stem cells,, Developmental Biology, Biology of Reproduction and Human Reproduction. His lab has been named one of the most important laboratories in embryonic stem cell research in China (N Engl J Med (2006) 355:1191-1194). With his achievements, Dr. Zhou has received numerous international and national awards such as the 1st SINO PRIX AJEFC Le Bioscience (2000, France), PRIX AFCRST Le Prix Tang Freres Biotechnologie (2002, France), the 3rd GenOway Prize for Transgenic Technologies (2004, Sweden), Bayer-CAS (2006, China), National Young People Award (2007, China).
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